Molecular characterization and functional analysis of the major autolysin of Staphylococcus aureus 8325/4.
نویسنده
چکیده
The gene encoding the major autolysin of Staphylococcus aureus 8325/4 has been cloned, sequenced, and insertionally inactivated. The three-domain, 137,384-Da protein has a C-terminal glucosaminidase active site and is involved in cell separation, generalized cell lysis, and release of wall material at the cell surface. Expression occurs throughout growth and is stimulated by low temperatures and in the presence of 1 M NaCl.
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 177 19 شماره
صفحات -
تاریخ انتشار 1995